Supplemental Videos for "Perivascular fibroblasts form the fibrotic scar after contusive spinal cord injury."

(view in full screen mode for better quality)

Fibroblasts-Vessels stack.mov

Movie 1: Perivascular fibroblasts and blood vessels in uninjured spinal cord. Consecutive serial optical sections obtained from uninjured mid-thoracic spinal cord of Col1a1-GFP transgenic mouse perfused with Lectin-Dylight 594. Perivascular fibroblasts are in green and vasculature is in red.

Fibroblasts-Vessels injured stack.mov

Movie 2: 3D reconstruction of perivascular fibroblasts in the uninjured spinal cord. This is a 3D reconstruction of the image stack shown in Movie 1 above. Fibroblasts are in green and blood vessels are in red.

Fibroblasts-Vessels normal.mov

Movie 3. Perivascular fibroblasts and blood vessels in the injured spinal cord. Consecutive serial optical sections obtained from the spinal cord injury site at 2 weeks after injury. This serial view shows fibroblasts detaching from blood vessels and accumulating at the injury site.

Fibroblasts-Vessels injured.mov

Movie 4. 3D reconstruction of perivascular fibroblasts in the injured spinal cord. This is a 3D reconstruction of the image stack shown in Movie 3 above. Fibroblasts are in green and blood vessels are in red.